V. Enteral Nutrition

A. Tube Placement Options

1. Nasoenteric Feeding Tubes

Tubes are passed through the nose to various points in the GI tract and are named with reference to the location of the terminal end of the feeding tube. Examples include nasogastric, nasoduodenal, and nasojejunal tubes.

2. Tube Enterostomy

Tubes are placed either laparoscopically, operatively, or percutaneously. Examples include esophagostomy, gastrostomy (PEG), percutaneous endoscopic jejunostomy (PEJ), needle catheter jejunostomy (NCJ), operative laparoscopic gastrostomy, operative laparoscopic jejunostomy.

B. Formula Selection

When selecting an appropriate enteral formulation both formula characteristics and patient-specific factors should be considered. Formula variables include: digestibility/availability of the nutrients, nutritional adequacy, viscosity, osmolality, ease of use, and cost. Patient variables include: nutritional status and requirements, electrolyte balance, digestive and absorptive capacity, disease state, renal function, medical or drug therapy, and possible routes available for administration. Adult enteral formula products fall into one of the following categories: general use, high nitrogen, high nitrogen and high calorie, fiber enriched, semi-elemental, fat modified, and specialty. Dietitians are available to assist with formula selection. HMC and UWMC RD's prepare and distribute enteral formulary pocket reference cards containing up-to-date product information for physician use.

C. Administration Guidelines


1. Initiation and Progression

To promote tolerance, enteral tube feedings should be initiated at rates of 50 cc/hr in adults. Most currently available formulas are isotonic (300 mOsm/L) and are well tolerated at full strength when delivered into the stomach or small intestine. The rate of administration of isotonic formulas can usually be advanced in 20-25 cc/hr increments every 8 hours until goal rate is achieved. It is often more realistic to calculate goal rates based on 20-22 hours/day allowing for interruptions in delivery.

2. Calculate Additional Free Water Requirements

Most patients on enteral nutrition therapy will require additional fluid to meet minimum fluid requirements. To calculate additional fluid requirements begin by determining the patient's total fluid needs (see Section III part D). Then determine the amount of free water provided by the tube feeding formula by multiplying the percent free water content (information available in diet manual, on enteral formulary cards, or by contacting a dietitian) by the total volume of tube feeding formula to be administered each day. Subtract the free water supplied by the formula from the calculated total free water requirement which equals remaining volume of free water and divide the remaining into 3 or 4 boluses per day.

Example:

A 50 year old female weighing 55 kg requires full strength Isosource HN at 55 mL/hr to meet her energy and protein requirements and 1800-2000 mL fluid/d. Isosource HN is 82% free water. Then 55 mL/hr x 24 hr x 0.82 = 1082 mL free water/d provided by the enteral formula. Her additional fluid needs are 1800 - 1082 = 718 mL/d or about 3 boluses of 250 mL each.

3. Transition to Cyclic or Bolus Feedings

Hospitalized patients may initially benefit from a continuous infusion to establish tolerance to enteral nutrition therapy and later transition to an intermittent infusion schedule. Intermittent infusion (bolus feedings) can be administered by gravity dip or syringe bolus for those patients with gastric feeding tubes.

Cyclic feeding using a pump can be used in patients with intestinal feeding tube sites (duodenum or jejunum). Cyclic feeding infuse formula for a set number of hours (e.g. 8-12 hours overnight). A cyclic feeding schedule should be considered for patients for whom free time off the pump is desired.

4. Vitamin and Mineral Requirements
Enteral formulations contain varying amounts of vitamins and minerals and may not be sufficient to meet patient needs. Consult a dietitian for the micronutrient content of specific products and for assistance in determining supplementation for these patients.

5. Monitoring

Routine nursing care includes checking gastric residuals every 4-6 hr in patients receiving gastric feedings until desired rate is established. Infusions are held for 1 hour if gastric residual is >(1.0 to 1.5) x hourly rate or >150 mL before bolus or intermittent feeding.

Daily weights, I/O records, serum electrolytes, phosphorus, magnesium, and ionized calcium should be monitored until tolerance is established and patient is stable (see Section VII).

D. Writing Enteral Nutrition Orders

E. Medications and Enteral Nutrition

The following are general guidelines for ordering and administering medications to patients receiving enteral nutrition.

F. Complications of Enteral Nutrition Therapy

Patients should be monitored frequently for evidence of complications from enteral nutrition support. Table III lists potential complications of tube feedings and offers suggestions for intervention.

Table III: Complications of Enteral Nutrition Therapy: Possible Causes & Management

Complications Possible Cause Suggested Management
Gastrointestinal
diarrhea (>4 BM
per day or large
loose stool)
medications
  • eliminate antibiotics or
    antacids if possible
  • eliminate liquid formulations
    containing sorbitol
  fat intolerance
  • change to low fat formula
  bacterial
overgrowth
  • stool culture for pathogens
  • Rx L. acidophilus/L.
    bulgaricus (LactinexTM if
    patients receiving antibiotics
  contaminated
formula
  • DC current formula
  • replace bag and tubing
    using aseptic techniques
  • adhere to clean standard when changing or manipulating feeds
  osmotic overload
  • decrease concentration of formula
  • change to isotonic formula
  • further dilute hypertonic
    medications
  • administer medications
    by alternate route
  decreased bulk
  • change to high fiber formula
  • administer bulking agents
    (e.g. psyllium) but not
    through small bore (10
    French) feeding tubes
nausea or vomiting patient position
  • position patient on right
    side fo facilitate passage
    of gastric contents through
    pylorus
  volume overload
  • decrease total volume
  • decrease delivery rate to
    one tolerated previously
  • advance delivery rate
    slowly over 12-24 hours
  delayed gastric
emptying
  • stop feeding for 2 hours
    & check residuals
  • change to low-fat formula
  • administer prokinetic
    agent (metoclopramide,
    cisapride) to stimulate GI
    motility
  specific nutrient
intolerances
  • change to lactose-free or
    low-fat formula
  GI tract
obstruction
  • stop feeding
constipation (no stool x
3 days
dehydration &
impaction
  • provide free water
  • remove impaction
  decreased fiber
  • change to fiber formula
  • administer bulking agents
    (e.g. psyllium) but not
    through small bore feeding
    tubes (<10 French)
  GI tract
obstruction
  • stop feeding
Mechanical
pulmonary aspiration patient lying flat
  • elevate head of bed 30 to 45
    degrees during continuous feeds
    or for 30 to 60 minutes
    after bolus feeds
  absent or depressed
gag reflex
  • infuse feedings into
    duodenum or jejunum
  reflux
  • change to smaller bore tube
    (<12 French) (large bore
    tube can reduce LES
    competence)
  • infuse feedings into
    duodenum or jejunum
  improper tube
placement
  • confirm proper placement by
    X-ray after insertion, after
    severe coughing, vomiting, or
    seizure
  • reconfirm placement prior to
    each feeding by checking
    residuals
  • tape tube in place & mark
    tube at exit point for
    reference
  • restrain patient if unable to
    keep from pulling
tube obstruction acid precipitation
of formula
  • flush tube with water before
    & after check gastric
    residuals
  • infuse feedings into
    duodenum or jejunum
  • do not mix medications with enteral formula
  insufficient tube
irrigation
  • flush tube with warm water
    before & after each bolus
    feeding, every 8 hours during
    continuous feeding, or
    whenever feeding is stopped
  medications
  • adequately crush medications
    and mix powder with water
  • use liquid medications where
    possible or administer by
    alternative route
  • flush tube before & after
    medication administration
    with at least 20 mL warm
    water
  • avoid administering bulk
    forming agents via small bore

    tubes

mucosal damage extended use of large bore tubes
  • alternate nares
  • change to small bore tube
    (<10 French)
  • change to a permanent
    gastrostomy or jejunostomy
    tube for extened enteral
    support
  • tape in place to minimize
    rubbing
Metabolic
overhydration refeeding
  • decrease delivery rate
  fluid overload
  • restrict free water
  • change to concentrated
    formula
  • administer diuretics
dehydration high osmolality
formula
  • change formula
  diarrhea
  • change formula
  • see able management of
    diarrhea
  excessive protein
intake with
inadequate fluid
intake
  • change decreased protein
    content formula
  • provide additional water
hyperglycemia insulin deficiency
  • give insulin (insulin drip used
    more successfully for enterally
    tube fed patients)
  • change formula to higher fat/
    lower carbohydrate content
  • change to high fiber formula
hypoglycemia sudden cessation of feedings
  • taper feedings
  • monitor blood sugar if
    feedings interrupted
hyperkalemia metabolic acidosis
  • reduce K intake/use reduced
    K formula
  • Rx KaexalateTM
  renal insufficiency
  • reduce K intake/use reduced
    K formula
  • Rx KaexalateTM
  anabolic
metabolism
  • reduce potassium intake/use
    reduced K formula
hypokalemia refeeding syndrome
  • monotor serum K daily and
    replete until stable
  insulin
administration
  • lower dose or discontinue
  diuretics
  • discontinue if possible
  diarrhea
  • see management above
hyperphosphatemia renal insufficiency
  • use reduced PO4 formula
  • administer phosphate binder
hypophosphatemia refeeding
syndrome, insulin
administration
  • monitor serum PO4 daily and
    replete until stable
hypomagnesemia refeeding syndrome,
alcoholism
  • monitor serum Mg daily and
    replete until stable
hyponatremia fluid overload
  • restrict free water
  • Use NS to flush tube and
    provide hydration instead of water
elevated BUN renal failure
excess protein
(nitrogen) intake
dehydration
medications
diuretics, steriods)
  • reassess medicadtions
  • increase free water
  • reassess renal function
  • reassess protein needs
rapid, excessive
weight gain
excess calories,
excess fluid,
electrolyte
imbalance
  • change formula or decrease
    delivery rate
  • evaluate electrolytes
insufficient weight gain inadequate calories
  • change formula or increase
    delivery rate
  malabsorption
  • change to semi-elemental
    formula
  catabolic state
  • provide nutrition support for
    weight maintenance while
    addressing medical issues
depression, withdrawal,
non-compliance
altered body image
  • encourage socialization at
    mealtimes
  • provide emotional support
  loss of oral
gratification
  • provide ice chips, sugar-free
    gum or hard candies
  • provide oral care every shift


Table of Contents | VI. Parenteral Nutrition