III. Estimating Nutritional Requirements (Adults)

A. Determine Usual or "Adjusted" Body Weight

If the patient is severely underweight (less than 80% of IBW) then use Current Weight for nutrient calculations.
If the patient is obese, use: Ideal body weight can be used for nutritional assessment purposes. See Appendix E for IBW tables based on height for males and females.

B. Energy Requirements

Most hospitalized patients will require 30 kcals/kg/d. Refer to Appendix F for detailed information on estimating energy requirements. Dietitians can also provide more refined estimates of nutrient requirements. At Harborview Medical Center, a metabolic cart is available for estimation of energy requirements. Overfeeding should be avoided.

C. Protein Requirements

Protein needs may vary greatly with the metabolic status of the patient. The average patient receiving nutritional intervention requires 0.8 _ 2.0 g protein/kg usual body weight. The obese patient is unusual. Use of usual body weight can result in overfeeding. It is recommended to use Adjusted Body Weight (ABW) for reasonable estimation of nutrient requirements. The goals of nutrition support are to minimize protein breakdown, preserve lean body mass, promote protein synthesis, and optimize immune responses. The factors listed in Table I can be used to estimate protein requirements.

Table I: Estimating Protein Requirements
Clinical Status Protein Requirements (g/kg/day)*
Maintenance 0.8-1.0
Mild to Moderate Depletion 1.0-1.5
Post-operative 1.2-2.0
*Note: Table based on usual body weight except in obese patients.

D. Fluid Requirements

A healthy adult ingests approximately 1 mL free water/kcal of energy, or 35-50 mL/kg body weight/day. Hospitalized patients usually require 30-35 mL/kg/day. Fluid needs may also be approximated as 1500 mL per m2BSA. However, wide variations in fluid intake are normally well tolerated without producing hypo- or hypernatremia or fluid overload. Patients with liver disease, renal failure, cardiac or pulmonary diseases or closed head injuries may require restricted fluid intakes while patients with nasogastric output, diarrhea, hypovolemia secondary to burns or trauma, diuresis, fistulae, and insensible losses may require additional fluids. Insensible losses are the result of respiration, fecal loss, evaporation, and fever. Replace diarrhea output volume per volume with normal saline, nasogastric or fistulous output with 1/2 normal saline, and evaporation due to fever (250 mL/day for each oC above 37oC) with sterile water or D5W.

Volume depleted patients should be rehydrated and electrolytes repleted before initiating PN, i.e. fluid deficits should not be corrected with amino acid and dextrose solutions. PN solutions are extremely hyperosmolar and cannot be converted to an equivalent iso-osmolar volume or volume of free water. Additional fluids (e.g. normal saline, sterile water) can be added directly to PN bags, some enteral feeding bags, or can be administered as boluses in tube fed patients.

E. Electrolyte Requirements

Electrolyte requirements for the average adult patient without significant cardiovascular, hepatic, or renal disease, or an underlying electrolyte abnormality, or significant electrolyte loss (e.g. fistulae) are shown in Table II. Electrolyte needs are adjusted daily based on lab results and current clinical status of the patient.

Table II: Typical Adult Baseline Electrolyte Requirements During Nutritional Repletion
Electrolyte Daily Requirements Comments
sodium (chloride, acetate, or phosphate) 60-150 mEq basal catabolism: 1-4 mEq/kg mild-moderate catabolism: 2-3 mEq/kg severe catabolism: 3-4 mEq/kg
potassium (chloride, acetate, or phosphate) 70-150 mEq basal catabolism: 0.7-0.9 mEq/kg mild-moderate catabolism: 2 mEq/kg severe catabolism: 3-4 mEq/kg
chloride (sodium or potassium) 60-150 mEq replaced 1 mEq per 1 mEq Na or K unless other salt form specified
magnesium (sulfate) 8-24 mEq monitor serum Mg concentration
phosphate (sodium or potassium) 7-10 mMol per 1000 kcal severe catabolism or prolonged absence of nutritional intake: 15-25 mMol per 1000 kcal of glucose

Nutritional repletion therapy increases electrolyte requirements. During the first 3 to 5 days of re-feeding, patients typically pass through three phases of electrolyte utilization. During the first 24 to 48 hours, total body deficits must be replaced. In the second phase, which may last for several days, anabolic processes are induced which result in increased intracellular uptake of potassium and phosphate. After approximately one week of providing nutritional therapy, electrolyte requirements become relatively stable.

F. Fat Requirements

A wide range of fat intake is generally well tolerated by most individuals. Current national guidelines recommend limiting fat intake to less than 30% of total kcals. A higher percent fat intake may be desired for patients with poor appetites/limited food intake to increase caloric density of foods (fat contains 9 kcal/g vs. 4 kcal/g in carbohydrates and protein). A minimum of 2-4% kcals as linoleic acid is required daily to prevent essential fatty acid deficiency. See Section VI: Initiating Parenteral Nutrition (page 25) for guidelines on parenteral lipid administration.

G. Micronutrient Requirements

Twelve vitamins and six trace elements are known to be essential in human metabolism (Appendix G). Hospital diets (except liquid diets) and enteral formulas are designed to provide at least the recommended daily allowance of each known essential nutrient.

Very little information is known about the micronutrient requirements of catabolic or hospitalized patients.


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