What are the most effective and best tolerated combination drug
therapies for essential hypertension?
Citations
BMJ Clinical Evidence
Cochrane Library
Search Cochrane Library -- Enter this strategy '(hypertension:ti or high blood pressure:ti) and (combination or combined or step) and (therapy or therapies or treatment or drugs)'
On results screen, under Systematic Reviews see:
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Antihypertensive drug therapy for mild to moderate hypertension during pregnancy .
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Oral beta-blockers for mild to moderate hypertension during pregnancy .
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Pharmacotherapy for hypertension in the elderly.
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Pharmacotherapy for hypertension in women of different races.
Under Protocols, see:
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Betablockers for hypertension (Protocol).
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Blood pressure lowering efficacy of calcium channel blockers for primary hypertension (Protocol).
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Blood pressure lowering efficacy of loop diuretics for primary hypertension (Protocol).
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Blood pressure lowering efficacy of thiazide diuretics for primary hypertension (Protocol).
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Comparison of calcium channel blockers with other classes of drugs for hypertension (Protocol).
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Comparison of pharmacological interventions for hypertension (Protocol).
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Dose-related blood pressure lowering efficacy of angiotensin converting enzyme inhibitors in the treatment of primary hypertension (Protocol).
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Dose-related blood pressure lowering efficacy of angiotensin receptor blockers in the treatment of primary hypertension (Protocol).
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Methyldopa in the management of essential hypertension (Protocol).
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Pharmacological interventions for hypertension (Protocol).
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Pharmacotherapy for hypertension in people of sub-Saharan Africa or of sub-Saharan African descent (Protocol).
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Reserpine for hypertension (Protocol).
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Treatment of hypertension in peripheral arterial disease (Protocol).
Under DARE, see:
- Angiotensin II antagonists for hypertension: are there differences in efficacy.
structured abstract of: Colin P R, Spence J D, Williams B, Ribeirao A B, Saito I, Benedict C, Bunt A M. Angiotensin II antagonists for hypertension: are there differences in efficacy. American Journal of Hypertension. 2000. 13(4 Part 1). 418-426.
- Are B-blockers efficacious as first-line therapy for hypertension in the elderly: a systematic review.
structured abstract of: Messerli F H, Grossman E, Goldbourt U. Are B-blockers efficacious as first-line therapy for hypertension in the elderly: a systematic review. JAMA. 1998. 279(23). 1903-1907.
- A comparison of blood lipid and blood pressure responses during the treatment of systemic hypertension with indapamide and with thiazides.
structured abstract of: Ames R P. A comparison of blood lipid and blood pressure responses during the treatment of systemic hypertension with indapamide and with thiazides. American Journal of Cardiology. 1996. 77(6). 12B-16B.
- Does drug treatment improve survival: reconciling the trials in mild-to-moderate hypertension.
structured abstract of: Hoes A W, Grobbee D E, Lubsen J. Does drug treatment improve survival: reconciling the trials in mild-to-moderate hypertension. Journal of Hypertension. 1995. 13(7). 805-811.
- Drug treatment of hypertension in the elderly: a meta-analysis.
structured abstract of: Insua J T, Sacks H S, Lau, T S et al. Drug treatment of hypertension in the elderly: a meta-analysis. Annals of Internal Medicine. 1994. 121(5). 355-362.
- Fixed-dose combination vs monotherapy in hypertension: a meta-analysis evaluation.
structured abstract of: Hilleman D E, Ryschon K L, Mohiuddin S M, Wurdeman R L. Fixed-dose combination vs monotherapy in hypertension: a meta-analysis evaluation. Journal of Human Hypertension. 1999. 13(7). 477-483.
- High blood pressure and diabetes mellitus: are all antihypertensive drugs created equal.
structured abstract of: Grossman E, Messerli F H, Goldbourt U. High blood pressure and diabetes mellitus: are all antihypertensive drugs created equal. Archives of Internal Medicine. 2000. 160. 2447-2452.
- Hypertension in the elderly: implications and generalizability of randomized trials.
structured abstract of: Mulrow C D, Cornell J A, Herrera C R, Kadri A, Farnett L, Aguilar C. Hypertension in the elderly: implications and generalizability of randomized trials. JAMA. 1994. 272(24). 1932-1938.
- Hypertension in the elderly: pressure to treat?.
structured abstract of: Sanderson S. Hypertension in the elderly: pressure to treat?. Health Trends. 1996. 28(4). 117-121.
- Meta-analysis of the long-term effect of nifedipine for pulmonary hypertension.
structured abstract of: Malik A S, Warshafsky S, Lehrman S. Meta-analysis of the long-term effect of nifedipine for pulmonary hypertension. Archives of Internal Medicine. 1997. 157. 621-625.
- Nebivolol in the management of essential hypertension: a review.
structured abstract of: McNeely W, Goa K L. Nebivolol in the management of essential hypertension: a review. Drugs. 1999. 57(4). 633-651.
- New meta-analysis of treatment trials of hypertension: improving the estimate of therapeutic benefit.
structured abstract of: Gueyffier F, Froment A, Gouton M. New meta-analysis of treatment trials of hypertension: improving the estimate of therapeutic benefit. Journal of Human Hypertension. 1996. 10(1). 1-8.
- Safety of nifedipine in patients with hypertension: a meta-analysis.
structured abstract of: Stason WB, Schmid CH, Niedzwiecki D, Whiting GW, Caubet J-F, Luo D, Ross SD, Chalmers TC. Safety of nifedipine in patients with hypertension: a meta-analysis. Hypertension. 1997. 30(1 Part 1). 7-14.
- Treatment of high blood pressure in patients aged over 60 years: lessons from randomized clinical trials.
structured abstract of: Lievre M, Leizorovicz A. Treatment of high blood pressure in patients aged over 60 years: lessons from randomized clinical trials. Cardiology in the Elderly. 1995. 3(3). 217-222.
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