FPIN Search
What are the most effective and best tolerated combination drug therapies for essential hypertension?

Clinician Author: Kerry Watrin
Librarian: Sarah Safranek

Search Summary

 

Resources Searched: Hits
number of (total)
Search Terms
Clinical Evidence 1 primary hypertension
18Sept2003
Cochrane Library Systematic Reviews (CDSR) 4
13 protocols
(hypertension:ti or high blood pressure:ti) and (combination or combined or step) and (therapy or therapies or treatment or drugs)
19Sept2003
Cochrane Library - Other Systematic Reviews (DARE) 14 same as CDSR
Bandolier 0 hypertension and combination
National Guideline Clearinghouse

5
(64 total)
hypertension and combination
18Sept2003
UpToDate 1 essential hypertension
PubMed Search: hypertension, antihypertensive agents, combination drug therapy
Systematic Reviews, Meta Analyses

  

34 (hypertension [mesh:noexp] AND antihypertensive agents [mh] AND (combination drug therapy [mh] OR drug combinations [mh])) AND (meta analysis [pt] OR meta analy* [tw] OR metaanaly* [tw] OR cochrane [tw] OR systematic review* [tw] OR medline [tw] OR embase [tw] OR "data synthesis" OR "data extraction" OR systematic [sb]) AND english [la]
PubMed Search: hypertension, antihypertensive agents, combination drug therapy
Randomized Controlled Trials: Double Blind Placebo

  

168 ((hypertension [mesh:noexp] AND antihypertensive agents [mh] AND (combination drug therapy [mh] OR drug combinations [mh])) AND ("double blind" OR "double blinded") AND (placebo OR placebos) AND (random* [tw] OR randomized controlled trial [pt] OR randomized controlled trials [mh]) AND english [la] NOT (meta analysis [pt] OR meta analy* [tw] OR metaanaly* [tw] OR cochrane [tw] OR systematic review* [tw] OR medline [tw] OR embase [tw] OR "data synthesis" OR "data extraction" OR systematic [sb])
PubMed Search: hypertension, antihypertensive agents, combination drug therapy
Other Randomized Controlled Trials

  

252 ((hypertension [mesh:noexp] AND antihypertensive agents [mh] AND (combination drug therapy [mh] OR drug combinations [mh])) AND (random* [tw] OR randomized controlled trial [pt] OR randomized controlled trials [mh]) AND english [la]) NOT (("double blind" OR "double blinded") AND (placebo OR placebos) OR (meta analysis [pt] OR meta analy* [tw] OR metaanaly* [tw] OR cochrane [tw] OR systematic review* [tw] OR medline [tw] OR embase [tw] OR "data synthesis" OR "data extraction" OR systematic [sb]))
PubMed Search - hypertension, antihypertensive agents, combination drug therapy
Guidelines, Consensus Statements
61 (hypertension [mesh:noexp] AND antihypertensive agents [mh] AND (combination drug therapy [mh] OR drug combinations [mh])) AND (guideline [pt] OR practice guideline [pt] OR guideline* [tw] OR consensus development conference, nih [pt] OR consensus development conference [pt] OR consensus [tw]) AND english [la]) NOT (meta analysis [pt] OR meta analy* [tw] OR metaanaly* [tw] OR cochrane [tw] OR systematic review* [tw] OR medline [tw] OR embase [tw] OR systematic [sb])
PubMed Search: hypertension (major MeSH), antihypertensive agents (major MeSH), combination drug therapy
Other Clinical Trials

122 (hypertension/drug therapy [majr:noexp] AND antihypertensive agents/therapeutic use [majr] AND (combination drug therapy [mh] OR drug combinations [mh]) AND (clinical trial [pt] OR treatment outcome [mh] OR outcome [tw] OR outcomes [tw] OR evidence-based [tw] OR trial [tw] OR trials [tw] OR multicenter [tw] OR multicentre [tw] OR "multi center" OR "multi centre")) NOT ("double blind" OR "double blinded" OR placebo* OR random* [tw] OR randomized controlled trial [pt] OR randomized controlled trials [mh] OR meta analysis [pt] OR meta analy* [tw] OR metaanaly* [tw] OR cochrane [tw] OR systematic review* [tw] OR medline [tw] OR embase [tw] OR "data synthesis" OR "data extraction" OR systematic [sb] OR guideline [pt] OR practice guideline [pt] OR guideline* [tw] OR consensus development conference, nih [pt] OR consensus development conference [pt] OR consensus [tw]) AND english [la]
PubMed Search: hypertension, combination or combined, therapy or treatment
"In Process" (new) citations

61 (hypertension AND (treatment OR therapy) AND (combination OR combinations) AND (treatment OR therapy OR manage OR management) AND (trial OR trials OR outcome* OR evidence-based OR "double blind" OR "double blinded" OR placebo* OR random* OR multicenter OR multicentre OR "multi center" OR "multi centre" OR guideline* OR consensus) AND english [la] AND premedline [sb]
PubMed searches run 29Sept2003

 

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Sarah Safranek, MLIS
Information Management Librarian

safranek@u.washington.edu
http://healthlinks.washington.edu/hsl/liaisons/safranek/